Step 1: In a large bowl, whisk together flour, cornmeal, and 1 teaspoon salt. Cut in the cold butter using a pastry blender or your fingertips until the mixture resembles coarse crumbs with some pea-sized pieces of butter remaining.
Step 2: Gradually add ice water, 1 tablespoon at a time, mixing until the dough just comes together. Do not overmix. Form into a disk, wrap in plastic, and refrigerate for at least 30 minutes.
Step 3: Preheat your oven to 425°F (220°C). If using a cast iron skillet, place it in the oven to preheat. In a large skillet, heat olive oil over medium-high heat. Add ground hamburger and Italian sausage. Cook, breaking up the meat with a spoon, until browned. Drain off any excess fat.
Step 4: Add chopped onion to the meat and cook until softened, about 5-7 minutes. Stir in minced garlic and cook for another minute until fragrant.
Step 5: Stir in crushed tomatoes, tomato paste, oregano, basil, red pepper flakes (if using), ½ teaspoon salt, and ¼ teaspoon black pepper. Bring to a simmer, then reduce heat and let it gently simmer for 15 minutes to allow flavors to meld. Remove from heat and stir in about half of the sliced pepperoni.
Step 6: On a lightly floured surface, roll out the chilled dough into a 14-inch circle. Carefully transfer the dough into a 10-inch deep dish pie pan or preheated cast iron skillet, pressing it firmly into the bottom and up the sides. Trim any excess dough, leaving about a ½-inch overhang.
Step 7: Layer half of the mozzarella and provolone cheese mixture over the bottom of the crust. Spoon the meat and sauce mixture evenly over the cheese. Top with the remaining mozzarella and provolone cheese, then arrange the remaining pepperoni slices over the top.
Step 8: Fold the overhanging dough inward, creating a rustic edge around the pie. Sprinkle with grated Parmesan cheese.
Step 9: Bake for 20 minutes at 425°F (220°C). Reduce oven temperature to 375°F (190°C) and continue to bake for another 30-35 minutes, or until the crust is golden brown and the cheese is bubbly and slightly browned. If the crust starts to brown too quickly, you can loosely cover the edges with aluminum foil.
Step 10: Remove from oven and let the pie rest for 10-15 minutes before slicing and serving. This allows the filling to set, making it easier to cut and serve.