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A close up shot of a slice of Mac and Cheese Meatloaf Casserole showing the distinct layers of meat and cheese.

The Ultimate Mac and Cheese Meatloaf Casserole


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  • Total Time: 70 minutes
  • Yield: 8 servings 1x
  • Diet: Classic Comfort

Description

A decadent and comforting hybrid dish featuring a savory meatloaf base topped with creamy, homemade macaroni and cheese.


Ingredients

Scale

2 lbs ground beef (80/20)
1 cup panko breadcrumbs
1/2 cup milk
2 large eggs
1 small onion, finely diced
3 cloves garlic, minced
1/2 cup ketchup
16 oz elbow macaroni
1/4 cup unsalted butter
1/4 cup all-purpose flour
3 cups whole milk
2 cups sharp cheddar cheese, shredded
1 cup mozzarella cheese, shredded
1 tsp salt
1/2 tsp black pepper


Instructions

Step 1: Preheat oven to 375°F and grease a 9x13 baking dish.
Step 2: Mix ground beef, breadcrumbs, 1/2 cup milk, eggs, onions, and garlic. Press into the bottom of the pan.
Step 3: Spread ketchup over the beef and bake for 25 minutes.
Step 4: Boil macaroni until al dente, then drain.
Step 5: Melt butter in a pan, whisk in flour, and gradually add 3 cups milk until thickened. Stir in cheese until melted.
Step 6: Mix pasta with cheese sauce and pour over the meatloaf layer.
Step 7: Bake for an additional 20-25 minutes until golden and bubbling.

Notes

Ensure you drain the grease after the first bake to keep the mac and cheese layer creamy and not oily.

  • Prep Time: 20 minutes
  • Cook Time: 50 minutes
  • Category: Main Course
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 1 slice
  • Calories: 650 kcal
  • Sugar: 6g
  • Sodium: 890mg
  • Fat: 38g
  • Saturated Fat: 18g
  • Unsaturated Fat: 14g
  • Trans Fat: 1g
  • Carbohydrates: 45g
  • Fiber: 2g
  • Protein: 35g
  • Cholesterol: 115mg
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