Step 1: Preheat your oven according to biscuit package directions, usually around 375°F (190°C). Prepare a baking sheet with parchment paper.
Step 2: In a medium bowl, combine the chopped cooked shrimp, lump crab meat, shredded cheese, mayonnaise or cream cheese (if using), garlic powder, salt, and black pepper. Mix gently until well combined.
Step 3: Open the can of biscuit dough. Separate each biscuit and flatten it slightly with your hands or a rolling pin to create a wider base, about 3-4 inches in diameter.
Step 4: Place a generous spoonful of the shrimp and crab mixture onto the center of half of the flattened biscuits. Top each filled biscuit with another flattened biscuit, gently pressing the edges together to seal. You can crimp the edges with a fork if desired to ensure the filling stays inside.
Step 5: Arrange the sealed biscuit melts on the prepared baking sheet. Brush the tops of each melt with melted butter.
Step 6: Bake for 18-20 minutes, or until the biscuits are golden brown and cooked through and the filling is hot and bubbly. Keep an eye on them to prevent overbrowning.
Step 7: Once out of the oven, sprinkle with fresh chopped parsley before serving warm. Enjoy!