Step 1: Cook the pasta in a large pot of salted boiling water according to package directions until al dente. Drain and rinse under cold water until completely cooled.
Step 2: In a small bowl, whisk together the mayonnaise, red wine vinegar, pepperoncini juice, dried oregano, garlic powder, salt, and pepper to create the dressing for the ultimate grinder pasta salad.
Step 3: In a large mixing bowl, combine the cooled pasta, salami, pepperoni, provolone, red onion, and sliced pepperoncinis.
Step 4: Pour the dressing over the pasta mixture and toss thoroughly until every ingredient is well coated.
Step 5: Gently fold in the shredded iceberg lettuce right before serving to maintain its crispness in the ultimate grinder pasta salad.
Step 6: Taste and adjust seasoning with extra salt, pepper, or a splash of vinegar if needed.